Using medical records, researchers tracked more than 13,000 people in a large northern California health plan from roughly their 40s and 50s into their 80s. Compared to people who had never been depressed, those who experienced symptoms of depression in middle age — but not later in life — were about 20% more likely to go on to develop dementia.
Those who received a depression diagnosis later in life only were at even greater risk. That group had about a 70% increased risk of dementia compared to their depression-free peers, according to the study, which was published this week in the Archives of General Psychiatry.
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