Coronary artery disease continues to be a major cause of death in the U.S., killing hundreds of thousands of people per year. However, this disease burden isn’t evenly divided between the sexes; significantly more men than women are diagnosed with coronary artery disease each year. The reasons behind this difference aren’t well defined. Though some studies have shown that men’s hearts become more constricted than women’s during exercise, letting less blood flow through, women are more likely than men to have symptoms of heart trouble after emotional upsets.
Searching for the reasons behind these disparities, Charity L. Sauder, Alison E. Thompson, Terrell Myers, and Chester A. Ray, all of Penn State College of Medicine, investigated the effects of mental stress on blood flow through the heart. Their findings show that coronary blood flow actually increases in men during mental stress, but shows no change in women. These results may explain why women could be more susceptible to adverse cardiac events when under stress.
An abstract of their study entitled, "Effect of Mental Stress on Coronary Blood Flow in Humans," was discussed at the meeting Experimental Biology 2012, held April 21-25 at the San Diego Convention Center.
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