Naltrexone: Injectable or oral?

Medications can help people who drink excessive amounts of alcohol. One medication that can reduce alcohol craving and help promote recovery is naltrexone, which is approved for treatment of alcohol dependence by the Food and Drug Administration. It is available in two forms — injectable and oral. This pilot study evaluated the feasibility of injectable versus oral naltrexone, administered in a hospital setting to enhance treatment compliance when patients leave the hospital.

Fifty-four veterans diagnosed with alcohol use disorder were recruited from a larger population of 113 veterans hospitalized for an acute medical or psychiatric illness. Participants were randomly divided into two groups: one received either 50-mg oral naltrexone for daily use plus a 30-day prescription; the other received a 380-mg intramuscular 30-day sustained release naltrexone injection prior to discharge, with a second injection one month later. Researchers followed up with both groups at 14 and 45 days following discharge.

Full story of injectable versus oral naltrexone at Science Daily

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Will Savage

Quantum Units Continuing Education provides online CEU training's to licensed professional mental health therapists, counselors, social workers and nurses. Our blog provides updates in the field of news and research related to mental health and substance abuse treatment.

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