Adolescent cannabis use alters development of planning, self-control brain areas

Adolescent marijuana use may alter how neurons function in brain areas engaged in decision-making, planning and self-control, according to researchers at the University of Illinois at Chicago.

The findings, which were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience, are the result of an animal model study focused on the structural development of the prefrontal cortex, or PFC, which controls high-level cognitive functions.

Within the PFC, a support structure called the perineuronal net forms a lattice of proteins around inhibitory cells, helping to secure their connections with excitatory neurons and regulate PFC activity. Perineuronal net formation is sensitive to drug use, but the effects of marijuana are not known.

Full story at Science Daily

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Will Savage

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