The number of emergency department visits involving the sleep drug zolpidem (the active ingredient in Ambien) almost doubled over four years, according to a new government report.
Zolpidem-related ER visits rose from 21,824 in 2005-2006, to 42,274 in 2009-2010, the Substance Abuse and Mental Health Services Administration (SAMHSA) found. In 2010, females accounted for two-thirds of zolpidem-related ER visits involving overmedication. The largest number of visits related to overmedication with the drug involved patients ages 45 to 54.
More than half of zolpidem-related ER visits also involved other prescription drugs, including other anti-anxiety and insomnia medications and narcotic pain relievers. In addition, 14 percent of visits involved alcohol combined with zolpidem.