Gastroesophageal reflux disease, known as GERD, can cause fatigue in people who have difficulty sleeping due to symptoms. For example, a person may repeatedly wake in the night to cough or because of pain associated with heartburn.
Medications for GERD can also have side effects that cause insomnia.
Results of a study published in 2013 suggest that there is a significant link between stress levels and inflammation caused by GERD. Stress and depression can also lead to sleepless nights.
Full story at Medical News Today