Many people have suggested that addiction hijacks the body’s natural drives in the service of compulsive drug use. A new study now suggests that hijacking another natural system in the brain may help overcome drug addiction. Published in Biological Psychiatry, the study shows that administration of oxytocin — a naturally occurring molecule well known for its role in social bonding and childbirth — reduces drug-seeking behavior in methamphetamine-addicted rats.
“There are virtually no pharmacotherapeutics for methamphetamine addiction, a chronically relapsing disease that destroys many lives,” said first author Dr. Brittney Cox, now at the University of California Irvine. “Our results are important because they support development of novel, oxytocin-based therapeutics for methamphetamine abuse in humans.”