Once a hip drug of the ’70s and ’80s party scene, cocaine is not only making a comeback, it’s proving its staying power thanks to its potent allure. In fact, Drug Enforcement Administration officials say that traffickers are producing more cocaine now than at the height of the notorious era of the “cocaine cowboys” in the 1980s.
According to Florida’s Medical Examiner Commission, overdose deaths from cocaine are at their highest level in the state since 2007. From 2012 to 2015, cocaine deaths in Florida increased from 1,318 fatalities to 1,834 fatalities. Only fentanyl, a powerful synthetic painkiller, surpassed deaths from cocaine overdose in Florida. Nationally, more than 1 in 3 drug misuse or abuse-related emergency department visits (40 percent) involved cocaine.
This highly addictive psychostimulant induces complex molecular, cellular and behavioral responses. Despite various approaches and years of pre-clinical studies, effective, mechanism-based therapies to assist with cocaine abuse and dependence are still sorely lacking.