cocaine

Brain’s ‘Dark Side’ as Key to Cocaine Addiction

Scientists at The Scripps Research Institute (TSRI) have found evidence that an emotion-related brain region called the central amygdala — whose activity promotes feelings of malaise and unhappiness — plays a major role in sustaining cocaine addiction. In experiments with rats, the TSRI researchers found signs that cocaine-induced changes in…

Drug Combination May Help Treat Cocaine Addiction, Study Suggests

A new study suggests combining the anti-seizure drug topiramate with amphetamines may help treat cocaine addiction. The Los Angeles Times reports topiramate has shown promise in treating nicotine and alcohol dependence, while amphetamines are used to treat attention deficit hyperactivity disorder. Both classes of drugs have been tested independently as…

Scientists Show Two-Drug Combination Has Potential to Fight Cocaine Addiction

A fine-tuned combination of two existing pharmaceutical drugs has shown promise as a potential new therapy for people addicted to cocaine—a therapy that would reduce their craving for the drug and blunt their symptoms of withdrawal. In laboratory experiments at The Scripps Research Institute, the potential therapy, which combines low…