glutamate

Neurotransmitter may play a role in alcohol relapse, addiction

A study led by Indiana University on neurochemical changes associated with alcohol addiction found that the neurotransmitter glutamate plays a role in some alcohol cravings. Alcohol dependence and alcohol use disorders occur in about 30 percent of all Americans, taking a severe toll on people’s lives, as well as on…

In rats that can’t control glutamate, cocaine is less rewarding, staving off relapse

Rats missing a neuroreceptor that controls the release of the neurotransmitter glutamate are less amenable to the rewarding effects of cocaine, increasing their chance of kicking the habit once addicted, researchers from the National Institute on Drug Abuse (NIDA) find. Their work, appearing July 11 in Cell Reports, suggests that the…