Scientists are working with three compounds that show promise in treating pain, without the side effects of opioids, CNBC reports.
One experimental drug, oliceridine, is in the final stages of human trials. It is administered intravenously. Studies show the drug relieves pain like morphine, without causing respiratory depression or constipation. However, it is no less addictive than morphine and it can only be used in hospitals. The company that makes oliceridine, Trevana, is developing an oral form of the drug.
Full story of new painkillers without side effects at drugfree.org
An experimental drug that relieves pain like morphine but is not addictive showed promise in a study of mice, the Los Angeles Times reports.
Stanford University researchers gave one group of mice the compound, called PZM21. A second group was given morphine. Both groups of mice were placed on a hot surface. PZM21 offered almost as much pain relief as morphine, and lasted for up to three hours—substantially longer than morphine, the researchers report in the journal Nature.
Full story of experimental non-addictive pain treatment at drugfree.org