pain treatment

Veterans benefit from pain treatment without drugs

A new study finds a lower risk of adverse post-treatment outcomes among returning military service personnel with chronic pain who received nondrug therapy. Many people returning from military deployment experience physical and mental health issues. These can include chronic pain, post-treatment alcohol use disorder, drug addiction, depression, thoughts of suicide, self-harm, or a combination.…

Adults who mix cannabis with opioids for pain report higher anxiety, depression

A researcher from the University of Houston has found that adults who take prescription opioids for severe pain are more likely to have increased anxiety, depression and substance abuse issues if they also use marijuana. “Given the fact that cannabis potentially has analgesic properties, some people are turning to it…

How cannabinoid drugs affect the experience of pain

A first-of-its-kind meta-analysis of existing research has reviewed the effects of cannabinoid drugs on the experience of pain. The Centers for Disease Control and Prevention (CDC) suggest that up to 50 million people in the United States have chronic pain. An increasing amount of people now turn to the medicinal benefits of cannabis for…

Study upends conventional view of opioid mechanism of action

A new discovery shows that opioids used to treat pain, such as morphine and oxycodone, produce their effects by binding to receptors inside neurons, contrary to conventional wisdom that they acted only on the same surface receptors as endogenous opioids, which are produced naturally in the brain. However, when researchers…

Kappa Opioid Receptor Structure Revealed, A Potential Milestone in Medication Development

New research funded by the National Institute on Drug Abuse illuminates the crystal structure of the activated kappa opioid receptor (KOR). The breakthrough could facilitate the development of new medications to treat pain and addiction. The KOR is activated by one of the body’s natural opioid molecules, called dynorphin. When…