New psychosis treatment targets genetic mutation instead of symptoms

A novel treatment that targets the biological effects of a specific genetic mutation could help alleviate the symptoms of psychosis, a new study finds.

Deborah L. Levy, Ph.D. — from the McLean Hospital in Belmont, MA — led the new study, the findings of which now appear in the journal Biological Psychiatry.

It revealed that people who had additional copies of a certain gene, instead of the regular two, benefited from the treatment.

The mutation, called a copy number variant (CNV), affects the glycine decarboxylase gene.

Full story at Medical News Today

Brain structure may play key role in psychosis

New research finds that having a larger choroid plexus, which is a vital brain structure, could be involved in psychosis.

Variations in the structure of the choroid plexus, which produces cerebrospinal fluid (CSF), could play a key role in psychosis.

A team that Dr. Paulo Lizano — of the Beth Israel Deaconess Medical Center in Boston, MA — led has now investigated this vital structure.

In doing so, they found that there could be a link between its size and the development of psychosis.

Full story at Medical News Today

AI can predict psychosis risk in everyday language

People’s language could reveal clues about their future risk of developing psychosis. Scientists concluded this after studying the subtle features of people’s everyday speech.

Researchers at Emory University in Atlanta, GA, and Harvard University in Boston, MA, used a machine-learning technique to analyze language in a group of at-risk young people.

They found that they could predict which individuals would go on to develop psychosis with an accuracy of 93%.

Full story at Medical News Today

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Could these food supplements help treat psychosis?

When added to standard early-stage treatment, certain food supplements may help to alleviate symptoms of psychotic illnesses such as schizophrenia.

This was the conclusion of a systematic review of data from eight trials involving hundreds of young people who received treatment during the early stages of psychosis.

The review was led by Dr. Joseph Firth, who is a research fellow with the NICM Health Research Institute at the University of Western Sydney in Australia and an honorary research fellow at the University of Manchester in the United Kingdom.

Full story at Medical News Today