Obesity associated with more rapid progression of disability in rheumatoid arthritis patients

In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a sign of frailty.

To examine the effects of obesity in patients with rheumatoid arthritis over time, Joshua Baker, MD, MSCE, of the Perelman School of Medicine at the University of Pennsylvania, and his colleagues examined information on 23,323 patients with rheumatoid arthritis from the National Data Bank of the Rheumatic Diseases and 1697 from the Veterans Affairs RA registry.

Full story at News-Medical.net

Drug Companies Seeking to Develop Less Addictive Pain Drugs

Pharmaceutical companies are working to develop less addictive pain drugs, according to the Associated Press.

Companies are researching drugs that target specific pathways and types of pain, instead of acting broadly in the brain. One example of this type of drug is Enbrel, which treats a key feature of rheumatoid arthritis.

Full story of less addictive pain drugs at drugfree.org