Out with the cigarette pack, put a cigarette in the mouth and light up. That is a well-known action for a smoker and, at the same time, behavior which has a stronger connection to actual drug dependency than was previously believed, research at the Sahlgrenska Academy has revealed.
“In the future we hope that this can contribute towards the development of pharmacological tools to help those who are dependent,” says Amir Lotfi Moghaddam, thesis defendant in addiction biology at the Institute of Neuroscience and Physiology.
In his pre-clinical thesis he has employed tests on rats in order to research factors which can be decisive in, for example, a party smoker becoming an habitual smoker. In addition to nicotine he has studied amphetamines. Both agents are centrally stimulating but have different molecular mechanisms.